Welcome to CFSource for Healthcare Professionals

A resource designed to help support your knowledge and help facilitate clinical conversations about cystic fibrosis (CF)

Understanding CF

Causes of CF

An overview of what causes CF, what cystic fibrosis transmembrane conductance regulator (CFTR) proteins do, and how mutations impact CF¹

CFTR Mutations

An explanation of the different kinds of CFTR mutations, their classes, and the importance of discussing CF genotype with patients and caregivers²

Multi-Organ Disease Progression

A review of how CF manifests beyond the lungs³

Managing CF

Go to CF Management in the First 2 Years of Life page

CF Management in the First 2 Years of a Child’s Life

Guidelines of treatment recommendations for managing CF in the first two years of life⁴

Resources

Helpful links for CF patients, caregivers, and their families

We want to hear from you!

In the future, we’d like to expand our resources to include more of what you’re looking for. Please let us know what types of content you're interested in seeing.

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References: 1. Derichs N. Targeting a genetic defect: cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis. Eur Respir Rev. 2013;22(127):58-65. doi:10.1183/09059180.00008412 2. Foil KE, Powers A, Raraigh KS, Wallis K, Southern KW, Salinas D. The increasing challenge of genetic counseling for cystic fibrosis. J Cyst Fibros. 2019;18(2):167-174. doi: 10.1016/j.jcf.2018.11.014 3. Elborn JS. Cystic fibrosis. Lancet. 2016;388(10059):2519-2531. doi:10.1016/S0140-6736(16)00576-6 4. Borowitz D, Robinson KA, Rosenfeld M, et al. Cystic Fibrosis Foundation evidence-based guidelines for management of infants with cystic fibrosis. J Pediatr. 2009;155(suppl 6):S73-93. doi:10.1016/j.jpeds.2009.09.001